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Week 1 of the 2022 NFL season was a thriller that featured some wild upsets. The Chicago Bears beat the San Francisco 49ers, the New York Giants pulled off an incredible comeback against the Tennessee Titans, and Russell Wilson lost in his return to Seattle. Expect even more craziness in Week 2, especially with some key injuries.

Thankfully, the experts at CBS Sports and SportsLine have you covered to guide you through this weekend’s slate. Every week, we’ll collect all the best picks and game content from CBSSports.com and SportsLine in one place, so you can get picks against the spread from our CBS Sports experts as well as additional content for every game, including games from top SportsLine experts and the SportsLine projection model, best bets from our staff, survivor picks and more.

All NFL odds via Caesars Sportsbook.

What choices can you make with confidence in Week 2? And which Super Bowl contender falls hard? Visit SportsLine, as their incredible model simulates every NFL game 10,000 times and has raised over $7,500 per $100 players on NFL’s top picks since its inception.

Tampa Bay Buccaneers at New Orleans Saints

Time: Sunday, 1:00 p.m. ET (Fox), broadcast on fuboTV (free trial) Open: Buccaneers -4, O/U 46. This may interest you : ‘More than video games’: York-area esports team enters fourth season.5

Featured game | New Orleans Saints vs Tampa Bay Buccaneers

“I don’t know why Tom Brady took 11 days off in the middle of training camp this year, but to me the most likely theory is that he did it so he could study the Saints defense for 264 hours straight without being interrupted.If there’s one team Brady hasn’t been able to figure out since signing from Tampa Bay, it’s definitely the Saints.

“Brady has faced the Saints four times in the regular season over the past two years, and not only has he gone 0-4 in those games, but the Buccaneers have lost all four games by multiple scores. In their second meeting of 2021 season, the Buccaneers lost 9-0, which is especially notable as it was the only time in the last 15 years that Brady was ruled out.

“When Brady announced he was coming back to the NFL after just 40 days out, I’m 99% sure his only reason for coming back was so he could beat the Saints. The good news for Brady is that this could finally be the year he can do it. If the Buccaneers want to win this game, their best bet might actually be to get it out of Brady’s hands. One of the reasons the Buccaneers are struggling against the Saints is that Brady is always under pressure I mean, the man is 45, if he’s running for his life every game, that’s not good for the Bucs.

“If Tampa can run the ball, they might be able to win, and based on what happened in Week 1, they might be able to do that. 200-plus YARDS rushing in Week 1 and that was against the FALCONS.(It was only the third time in the past five years that the Saints have allowed a team to cross the 200-yard rush mark. ) On the Buccaneers side, they actually ran the ball pretty well in Week 1 with Leonard Fournette rushing for 127 yards.

“I think the Saints can win, but I hate betting against Brady, which means I have to go with the Buccaneers.”

John Breech creates CBS Sports’ Most Entertaining Picks column each week. To see his other top picks for Week 2, click here.

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Carolina Panthers at New York Giants

Time: Sunday, 1:00 p.m. ET (Fox), streaming on fuboTV (free trial) Open: Giants -1. To see also : The global video game market is expected to decline for the first time since 2015.5, O/U 43

Featured game | New York Giants vs. Carolina Panthers

Parlays are a way to increase your payout by correctly predicting the outcome of two bets. Before you make your Week 2 NFL picks and NFL parlays, you need to see what the SportsLine projection model has to say. The model, which simulates every NFL game 10,000 times, has grown more than $7,500 for players to $100 on top NFL picks since its inception. The model enters Week 2 of the 2022 NFL season on an incredible 139-98 run on NFL’s top picks that dates back to the 2017 season.

This week he created a five-team bet, and the model actually likes the Giants to cover the small gap to the Panthers. Saquon Barkley and Co. picked up an upset victory in Nashville last week, and the Giants have some momentum for them as they prepare for their home opener. To see what else the model is enjoying this week, head to SportsLine.

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Miami Dolphins at Baltimore Ravens

Time: Sunday, 1:00 p.m. ET (CBS), streaming on Paramount+ (click here) Open: Ravens -3. This may interest you : Why make real progress in the NFL off-season.5, O/U 46

Featured game | Baltimore Ravens vs. Miami Dolphins

“The Dolphins and Ravens both won impressively last week, but now Miami hits the road for the first time. The Dolphins outplayed the Ravens last year at home, but it will be different. The Ravens and Lamar Jackson get the best of the Dolphins.”

CBS Sports senior NFL columnist Pete Prisco rolls with the Ravens to cover against the Dolphins this week. To see his breakdown of each match in Week 2, click here.

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New York Jets at Cleveland Browns

Time: Sunday, 1:00 p.m. ET (CBS), streaming on Paramount+ (click here)Open: Browns -4.5, O/U 43.5

Featured game | Cleveland Browns vs. New York Jets

“The Browns can definitely beat bad teams based on their defense and running game, and they had the opportunity to do that last week. But the defense crumbled in the fourth quarter and it took a 58-yard field goal to rookie Cade York just to escape with a win. In this case, I’m surprised they were set up as six-point favorites against anyone, and that line is even more high in some places. Is the market really going to give us the chance to catch a full touchdown against Jacoby Brissett? He’s made at least 60% of the snaps in 37 games in his career and won by more than six points only six times in those games, and four of those wins have come against the same team (Houston). How can we trust him as the heavy favorite?”

R. J. White has been SportsLine’s No. 1 NFL ATS expert for the past five years, going 445-378-24 ATS to give him 25+ units on those picks at SportsLine. He’s also had a 56.8% pass rate on his SuperContest selections over the past seven seasons, and that streak includes two cash finishes, including an 18th-place finish out of 2,748 entries in 2017.

He likes the Jets to cover the number there. To read his reasoning and find out about his other SuperContest picks, head over to SportsLine.

Washington Commanders at Detroit Lions

Time: Sunday, 1:00 p.m. ET (Fox), streaming on fuboTV (free trial) Open: PICK, O/U 44.5

Featured game | Detroit Lions vs. Washington Commanders

“It’s finally happened. For the first time in 24 games, the Lions are favored. Do they deserve it though? Detroit lost to Philly in Week 1 by three points, as a 14-0 run at the fourth quarter allowed the Lions to cover the lead. D’Andre Swift looked incredible as he racked up 175 yards from scrimmage, but the defense struggled to contain Jalen Hurts and Co.

“This Washington offense looked refreshed in Week 1. The Jacksonville Jaguars don’t have an elite defense, but I mean, Carson Wentz has some guns to work with. Antonio Gibson racked up 130 yards from scrimmage, Terry McLaurin grabbed a touchdown, Curtis Samuel grabbed a touchdown, then rookie wide Jahan Dotson grabbed two touchdowns in his NFL debut.The Lions struggled to contain A.J. Brown last week, who caught 10 passes for 155 yards. How is this unit going to handle multiple wide receivers that can impact I expect a lot of points in this game, but I like Washington to win.”

Jordan Dajani thinks the wrong team is favored in this game. For his other top four games this week in the NFL, click here.

Indianapolis Colts at Jacksonville Jaguars

Time: Sunday, 1:00 p.m. ET (CBS), streaming on Paramount+ (click here)Open: Colts -4.5, O/U 46

Featured game | Jacksonville Jaguars vs. Indianapolis Colts

“They haven’t won against (the Jaguars) on the road since 2014, and they had a chance to go to the playoffs last year and win, and didn’t in the last week of the game. season. So I just think it’s a tough place for the Colts. You go on the road, you play against the Texans, you go home, now you have to go on the road and play against a team that’s sitting at home, playing their first game at home. So I think that’s a big advantage for Jacksonville. I think their run defense will be much better this year. They’ll limit Jonathan Taylor. I don’t think you’ll need points, I think Jacksonville wins this game.

That’s Pete Prisco’s take on the Pick Six podcast, where he, Will Brinson and R.J. White broke down each game from a play perspective and gave out the best bets on Friday – as they do every week. Listen to it below and subscribe daily for great NFL content in your feed.

New England Patriots at Pittsburgh Steelers

Time: Sunday, 1:00 p.m. ET (CBS), streaming on Paramount+ (click here)Open: Patriots -1, O/U 43.5

Featured game | Pittsburgh Steelers vs. New England Patriots

“New England’s offense continues to look scrappy, and now they’re dealing with a down Mac Jones after he suffered a back injury in the opener against Miami. His status for this game n It’s not really in question, but one wonders if he’ll be limited at all as the Patriots head to Pittsburgh. While the Steelers will be without star pass-rusher T.J. Watt (pectoral), they still have a defense that should give to this Pats offense adjustments because they’re still looking to forge an identity Yeah, Pittsburgh’s offensive line is also a huge question, and their offense didn’t exactly light it up in the first win, but it just more playmakers than the Patriots at this point. a dog at home, it’s hard not to lean that way. New England also goes to Pittsburgh on an 0-4 ATS streak on the road.

Tyler Sullivan is our resident Patriots pundit, so he knows what he’s talking about in this game. He likes the Steelers this week. For his other top picks for Week 2, click here.

Seattle Seahawks at San Francisco 49ers

Time: Sunday, 4:05 p.m. ET (Fox), streaming on fuboTV (free trial) Open: 49ers -7.5, O/U 44.5

Featured game | San Francisco 49ers vs. Seattle Seahawks

“Quite shocking how that line has evolved based on these NFC West rivals’ respective Week 1 results. Seattle looked great against the Broncos, stealing a win from Russ and Denver. The 49ers suffered a stunning loss in Chicago, albeit one that took place in a seldom-seen monsoon.The weather certainly warrants giving Trey Lance and the offense an assist, though it hasn’t exactly stopped Justin Fields and the Bears from finding points in the second half. Pete Carroll has had a lot of success against San Francisco over the past half-decade, and the Seahawks look legitimately great.”

New Seahawks fan Will Brinson likes Seattle staying close this week and going 2-0 ATS. For its breakdown of gambling for each week 2 game, click here.

Atlanta Falcons at Los Angeles Rams

Time: Sunday, 4:05 p.m. ET (Fox), streaming on fuboTV (free trial) Open: Rams -13.5, O/U 50

Featured game | Los Angeles Rams vs. Atlanta Falcons

“The Rams will have been rested for 10 days after a terrible performance against the Bills. Sean McVay is too good a coach for this loss to linger. The Falcons played well losing to the Saints in a game they probably would have had to win. It’s a long road trip against a good team that will be focused. The Rams are taking matters into their own hands.

CBS Sports senior NFL columnist Pete Prisco takes the Rams on the rebound from their Week 1 loss. Check out his breakdown of every Week 2 game here.

Arizona Cardinals at Las Vegas Raiders

Time: Sunday, 4:25 p.m. ET (CBS), streaming on Paramount+ (click here)Open: Raiders -2.5, O/U 50.5

Featured game | Las Vegas Raiders vs. Arizona Cardinals

“Las Vegas didn’t post as many points as hoped, but moved the ball up and down the field on what could be some quality Chargers defense. Five sacks and three picks held them back, but the Cardinals defense looked flabby and unimposing. The Raiders averaged 7.33 yards per first play last week. That was pretty impressive, and Carr will learn not to favor Adams as much. The Raiders will generate pressure against a Cardinals suspect offensive line, and I got to see this Chandler Jones revenge game unfolding as well as Khalil Mack’s revenge game against the Raiders last week Vegas can also run the ball Cardinals are still a bit beaten, and I’m not getting a good vibe from them. Give me Raiders 3.5 touchdowns for +100 as well.”

SportsLine NFL Insider Jason La Canfora envisions the Raiders bouncing back this Sunday. To see his other top games from Week 2, head over to SportsLine.

Cincinnati Bengals at Dallas Cowboys

Time: Sunday, 4:25 p.m. ET (CBS), streaming on Paramount+ (click here) Open: Cowboys -1, O/U 52

Featured game | Dallas Cowboys vs. Cincinnati Bengals

“Cincinnati had a minus-five turnover and would still have beaten the Steelers if it weren’t for kicking disasters. The Bengals had 32 first downs. Dallas, on the other hand, looked baffled even before Dak Prescott’s injury Plus the Cowboys lost left guard Connor McGovern and safety Jayron Kearse to weeks-long injuries Bengals No. 2 Tee Higgins (concussion) is on track to play after taking part in a limited practice on Wednesday. Return Joe Burrow to bounce back from that four interceptions debacle as Cincy covers a short teaser number.”

NFL play expert Larry Hartstein, who entered 2022 with over 37 units on his NFL secondary picks for SportsLine, has officially dropped his teaser picks for Week 2. As you can see, he likes to take the Bengals from -7.5 to -1.5. For his other teasers, head over to SportsLine.

Houston Texans at Denver Broncos

Time: Sunday, 4:25 p.m. ET (CBS), streaming on Paramount+ (click here)Open: Broncos -10.5, O/U 42

Featured game | Denver Broncos vs. Houston Texans

The Broncos suffered an upset loss to the Seahawks in Week 1, but with that emotional showdown out of the way, Russell Wilson and Co. can now settle in and focus on becoming the AFC contender. that many consider them to be. At home in Week 2 against an inferior team, we got to see fireworks from the Broncos offense. Denver could be a good Survivor pick this week if you didn’t fall into the trap of picking them in Week 1.

For more picks and tips for Survivors, check out R.J. White’s Weekly Breakdown, here.

Chicago Bears at Green Bay Packers

Time: Sunday, 8:20 p.m. ET (NBC), broadcast on fuboTV (free trial)Open: Packers -8.5, O/U 44

Featured game | Green Bay Packers vs. Chicago Bears

Before making Bears vs Packers picks or any other NFL predictions, you need to see which side NFL expert R.J. White is on. White, a fantasy and games editor for CBS Sports, consistently crushes as SportsLine’s #1 NFL expert in picks against the spread, and went 445-378-24 on his 2017- 21, which grossed $2,542 at $100 players. He also went a whopping 51-17-1 on his NFL picks involving the Packers, meaning he’s well qualified for this selection.

We can tell you he’s leaning into the total, but for his official pick against the spread, you’ll have to head to SportsLine.

Tennessee Titans at Buffalo Bills

Time: Monday, 7:15 p.m. ET (ESPN), streaming on fuboTV (free trial)Open: Bills -7.5, O/U 52

Featured game | Buffalo Bills vs. Tennessee Titans

Former editor of Covers and The Linemakers, Larry Hartstein combines an extensive network of Vegas sources with an analytical approach he honed while working for Pro Football Focus. Going into the 2022 NFL season, he has an all-time 427-344 record on NFL sides (plus $3,764 for $100 players), including 394-330 ATS. Hartstein was 68-50 ATS (58%) and 8-3 on Money Line plays last season for a profit of $1,552. Everyone who followed him is upstairs. Additionally, Hartstein has gone 23-12-1 on his last 36 picks involving the Titans, netting $1,007.

We can tell you he’s looking at the total, but to see his pick against the spread, head to SportsLine.

Minnesota Vikings at Philadelphia Eagles

Time: Monday, 8:30 p.m. ET (ABC), streaming on fuboTV (free trial)Open: Eagles -2.5, O/U 48

Featured game | Philadelphia Eagles vs. Minnesota Vikings

SportsLine expert Emory Hunt is the founder and CEO of Football Gameplan, which has been providing analysis of all levels of football since 2007. He is a former running back at Louisiana-Lafayette and knows the game from the perspective of a player. Hunt went 35-20-1 on his last 56 picks involving the Eagles, netting $1,281. Everyone who followed him is upstairs.

We can tell you he’s looking at the total, but for his official pick against the spread, head to SportsLine.

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