For one study, researchers attempted to examine the associations of lifestyle factors with weight and awareness of amyloid in the mind. They focused on 178 intellectually typical individuals (women, 49%; 65.0 [7.6] years) and 54 individuals with mild intellectual disabilities (women, 35%; 71.3 [8.3] years) who signed up for an upcoming study of workers who completed 18F – Flutemetamol Amyloid Positron Effluent Imaging. Using the underlying state indicator, they examined the relationship between idle states, which deal with metabolic/vascular play, actual work and mental activity, with global amyloid weight and mental performance. The investigators also looked at the effects of gender in this model. In general, higher mental activity was associated with better mental execution, and higher actual work was associated with lower amyloid weight. The latter membership was weakened to a non-significant level after excluding multivariate exceptions. Assessing the driving influence of gender in the model revealed an inverse relationship between metabolic/vascular gambling and consciousness in men. In contrast, in women, the metabolic/vascular game moved toward increased amyloid weight. In addition, a large backward relationship has been found between labor-intensive work and amyloid weight, especially in men. Inheritance of an APOE4 allele was associated with higher amyloid weight only in females. Sex alters the effects of a particular lifestyle on amyloid weight and understanding. Their results suggest that the adverse consequences of metabolic/vascular gambling specifically contribute to gambling in mental decline and Alzheimer’s disease affect women and men.
Source: onlinelibrary.wiley.com/doi/10.1002/ana.26417
Does Alzheimer’s affect more gender?
Women are disproportionately affected by Alzheimer’s disease (AD). Almost two-thirds of the more than 5 million Americans living with Alzheimer’s are women, and two-thirds of the more than 15 million Americans who care for and support someone with Alzheimer’s are women.
Why is Alzheimer’s more common in females than males?
Women have stronger immune systems than men. As part of their stronger immune systems, women can end up having more amyloid plaques than men. Since they may have more amyloid plaques than men, this theory could explain why women ultimately have a higher risk of developing Alzheimer’s.
